2P3L
Crystal Structure of Dengue Methyltransferase in Complex with GpppA and S-Adenosyl-L-Homocysteine
Summary for 2P3L
Entry DOI | 10.2210/pdb2p3l/pdb |
Related | 1L9K 2P1D 2P3O 2P3Q 2P40 2P41 |
Descriptor | type II methyltransferase, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total) |
Functional Keywords | vizier; viral enzymes involved in replication; dengue virus methyltransferase; structural genomics; marseilles structural genomics program @ afmb; msgp, viral protein, transferase |
Biological source | Dengue virus 2 |
Cellular location | Envelope protein E: Virion membrane; Multi- pass membrane protein: Q9WLZ8 |
Total number of polymer chains | 1 |
Total formula weight | 36318.38 |
Authors | Egloff, M.P.,Marseilles Structural Genomics Program @ AFMB (MSGP) (deposition date: 2007-03-09, release date: 2007-08-28, Last modification date: 2023-08-30) |
Primary citation | Egloff, M.P.,Decroly, E.,Malet, H.,Selisko, B.,Benarroch, D.,Ferron, F.,Canard, B. Structural and functional analysis of methylation and 5'-RNA sequence requirements of short capped RNAs by the methyltransferase domain of dengue virus NS5 J.Mol.Biol., 372:723-736, 2007 Cited by PubMed: 17686489DOI: 10.1016/j.jmb.2007.07.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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