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2OGM
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BU of 2ogm by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-571519
Descriptor: (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE, 23S ribosomal RNA, 50S ribosomal protein L3
Authors:Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGO
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BU of 2ogo by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative retapamulin (SB-275833)
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L3, Retapamulin
Authors:Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.66 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGN
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BU of 2ogn by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-280080
Descriptor: (3AS,4R,5S,6S,8R,9R,9AR,10R)-5-HYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROPANOCYCLOPENTA[8]ANNULEN-8-YL (PIPERIDIN-4-YLTHIO)ACETATE, 23S ribosomal RNA, 50S ribosomal protein L3
Authors:Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
Deposit date:2007-01-07
Release date:2007-05-01
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.56 Å)
Cite:Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
4X3B
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BU of 4x3b by Molmil
A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Roedig, P, Vartiainen, I, Duman, R, Panneerselvam, S, Stuebe, N, Lorbeer, O, Warmer, M, Sutton, G, Stuart, D.I, Weckert, E, David, C, Wagner, A, Meents, A.
Deposit date:2014-11-28
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering.
Sci Rep, 5, 2015
4X35
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BU of 4x35 by Molmil
A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Roedig, P, Vartiainen, I, Duman, R, Panneerselvam, S, Stuebe, N, Lorbeer, O, Warmer, M, Sutton, G, Stuart, D.I, Weckert, E, David, C, Wagner, A, Meents, A.
Deposit date:2014-11-27
Release date:2015-06-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering.
Sci Rep, 5, 2015
5FB6
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BU of 5fb6 by Molmil
Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering
Descriptor: Insulin Chain A, Insulin Chain B
Authors:Roedig, P, Duman, R, Sanchez-Weatherby, J, Vartiainen, I, Burkhardt, A, Warmer, M, David, C, Wagner, A, Meents, A.
Deposit date:2015-12-14
Release date:2016-06-15
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering.
J.Appl.Crystallogr., 49, 2016
5NE0
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BU of 5ne0 by Molmil
Room temperature in-situ structure of hen egg-white lysozyme from crystals enclosed between ultrathin silicon nitride membranes
Descriptor: CHLORIDE ION, Lysozyme C, SODIUM ION
Authors:Martiel, I, Opara, N, Arnold, S.A, Braun, T, Stahlberg, H, Makita, M, David, C, Padeste, C.
Deposit date:2017-03-09
Release date:2017-06-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers.
J.Appl.Crystallogr., 50, 2017
2W85
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BU of 2w85 by Molmil
Structure of Pex14 in complex with Pex19
Descriptor: PEROXIN-19, PEROXISOMAL MEMBRANE ANCHOR PROTEIN PEX14
Authors:Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M.
Deposit date:2009-01-09
Release date:2009-02-17
Last modified:2013-05-08
Method:SOLUTION NMR
Cite:Structural Basis for Competitive Interactions of Pex14 with the Import Receptors Pex5 and Pex19.
Embo J., 28, 2009
2W84
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BU of 2w84 by Molmil
Structure of Pex14 in complex with Pex5
Descriptor: PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR
Authors:Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M.
Deposit date:2009-01-09
Release date:2009-02-17
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
EMBO J., 28, 2009
5MQW
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BU of 5mqw by Molmil
High-speed fixed-target serial virus crystallography
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A.
Deposit date:2016-12-21
Release date:2017-06-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
5OSN
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BU of 5osn by Molmil
Crystal Structure of Bovine Enterovirus 2 determined with Serial Femtosecond X-ray Crystallography
Descriptor: Capsid protein, GLUTAMIC ACID, POTASSIUM ION, ...
Authors:Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Kotecha, A, Kelly, J, Rowlands, D.J, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A.
Deposit date:2017-08-17
Release date:2017-08-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
6V3X
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BU of 6v3x by Molmil
Crystal structure of EED in complex with PALI1-K1241me3 peptide
Descriptor: PALI1 peptide, Polycomb protein EED
Authors:Zhang, Q, Davidovich, C.
Deposit date:2019-11-26
Release date:2021-05-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
6V3Y
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BU of 6v3y by Molmil
Crystal structure of EED in complex with PALI1-K1219me3 peptide
Descriptor: PALI1 peptide, Polycomb protein EED
Authors:Zhang, Q, Davidovich, C.
Deposit date:2019-11-26
Release date:2021-05-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
3JQ4
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BU of 3jq4 by Molmil
The structure of the complex of the large ribosomal subunit from D. Radiodurans with the antibiotic lankacidin
Descriptor: 23S ribosomal RNA, 5S ribosomal RNA, N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide
Authors:Auerbach-Nevo, T, Mermershtain, I, Davidovich, C, Bashan, A, Rozenberg, H, Yonath, A.
Deposit date:2009-09-06
Release date:2010-09-08
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.52 Å)
Cite:The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics
Proc.Natl.Acad.Sci.USA, 107, 2010
3FWO
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BU of 3fwo by Molmil
The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin
Descriptor: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA
Authors:Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A.
Deposit date:2009-01-19
Release date:2010-01-19
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Biotechnologia, 1, 2009
1DRB
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BU of 1drb by Molmil
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
Authors:David, C, Kraut, J.
Deposit date:1991-11-06
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
5M7M
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BU of 5m7m by Molmil
Novel Imidazo[1,2-a]pyridine Derivatives with Potent Autotaxin/ENPP2 Inhibitor Activity
Descriptor: CHLORIDE ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, IODIDE ION, ...
Authors:Wolhkoning, A, Fleury, D, Leonard, P, Triballeau, N, Mollat, P, Vercheval, L.
Deposit date:2016-10-28
Release date:2017-08-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.
J. Med. Chem., 60, 2017
4U67
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BU of 4u67 by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22
Descriptor: 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
Deposit date:2014-07-28
Release date:2015-08-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
4WFN
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BU of 4wfn by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin
Descriptor: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
Deposit date:2014-09-16
Release date:2015-12-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.54 Å)
Cite:The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
7PKO
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BU of 7pko by Molmil
CryoEM structure of Rotavirus NSP2
Descriptor: Non-structural protein 2
Authors:Bravo, J.P.K, Borodavka, A.
Deposit date:2021-08-26
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PKP
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BU of 7pkp by Molmil
NSP2 RNP complex
Descriptor: Non-structural protein 2
Authors:Bravo, J.P.K, Borodavka, A.
Deposit date:2021-08-26
Release date:2021-09-29
Last modified:2021-10-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Proc.Natl.Acad.Sci.USA, 118, 2021
6R95
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BU of 6r95 by Molmil
The solution NMR structure of cis-dicarba-brevinin-1BYa in 33% trifluoroethanol
Descriptor: Brevinin-1BYa
Authors:Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
Deposit date:2019-04-02
Release date:2019-09-25
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
6R96
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BU of 6r96 by Molmil
The solution NMR structure of cis-dicarba-brevinin-1BYa in sodium dodecyl sulphate micelles
Descriptor: Brevinin-1BYa
Authors:Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
Deposit date:2019-04-02
Release date:2019-09-25
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
6G4U
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BU of 6g4u by Molmil
The solution NMR structure of brevinin-1BYa in dodecylphosphocholine micelles
Descriptor: Brevinin-1BYa
Authors:Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
Deposit date:2018-03-28
Release date:2019-10-16
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments.
J.Pept.Sci., 25, 2019
6G4I
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BU of 6g4i by Molmil
The solution NMR structure of brevinin-1BYa in 33% trifluoroethanol
Descriptor: Brevinin-1BYa
Authors:Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
Deposit date:2018-03-27
Release date:2019-10-09
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments.
J.Pept.Sci., 25, 2019

 

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