2W84

Structure of Pex14 in complex with Pex5

Summary for 2W84

• Entry DOI: 10.2210/pdb2w84/pdb
• Related: 1FCH 2C0L 2C0M 2J9Q 2W85
• Descriptor: PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR (2 entities in total)
• Functional Keywords: zellweger syndrome, alternative splicing, phosphoprotein, protein complex, disease mutation, peroxisome, tpr repeat, polymorphism, translocation, peroxisome biogenesis disorder, protein transport, peroxisome import, pts, receptor-cargo complex, peroxisome targeting signal
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: P50542
• Total number of polymer chains: 2
• Total formula weight: 9716.86

Authors

Neufeld, C.,Filipp, F.V.,Simon, B.,Neuhaus, A.,Schueller, N.,David, C.,Kooshapur, H.,Madl, T.,Erdmann, R.,Schliebs, W.,Wilmanns, M.,Sattler, M. (deposition date: 2009-01-09, release date: 2009-02-17, Last modification date: 2018-01-17)

• Primary citation: Neufeld, C.,Filipp, F.V.,Simon, B.,Neuhaus, A.,Schuller, N.,David, C.,Kooshapur, H.,Madl, T.,Erdmann, R.,Schliebs, W.,Wilmanns, M.,Sattler, M.; Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.; EMBO J., 28:745-754, 2009; PubMed: 19197237; DOI: 10.1038/emboj.2009.7

Experimental method

SOLUTION NMR