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3TMP
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BU of 3tmp by Molmil
The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde
Descriptor: OTU domain-containing protein 5, Polyubiquitin-C
Authors:Ma, X, Yin, J, Hymowitz, S, Starovasnik, M, Cochran, A.
Deposit date:2011-08-31
Release date:2012-01-11
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Phosphorylation-dependent activity of the deubiquitinase DUBA.
Nat.Struct.Mol.Biol., 19, 2012
3K48
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BU of 3k48 by Molmil
Crystal structure of APRIL bound to a peptide
Descriptor: Tumor necrosis factor ligand superfamily member 13, peptide
Authors:Hymowitz, S.G.
Deposit date:2009-10-05
Release date:2009-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Multiple novel classes of APRIL-specific receptor-blocking peptides isolated by phage display.
J.Mol.Biol., 396, 2010
2HFF
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BU of 2hff by Molmil
Crystal structure of CB2 Fab
Descriptor: CB2 Fab, heavy chain, light chain
Authors:Hymowitz, S.G.
Deposit date:2006-06-23
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood, 108, 2006
2HFG
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BU of 2hfg by Molmil
Crystal structure of hBR3 bound to CB3s-Fab
Descriptor: CB3s Fab heavy chain, CB3s Fab light chain (kappa), Tumor necrosis factor receptor superfamily member 13C
Authors:Hymowitz, S.G.
Deposit date:2006-06-23
Release date:2006-11-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Synthetic anti-BR3 antibodies that mimic BAFF binding and target both human and murine B cells.
Blood, 108, 2006
5CVM
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BU of 5cvm by Molmil
USP46~ubiquitin BEA covalent complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, ZINC ION
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2015-11-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CVL
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BU of 5cvl by Molmil
WDR48 (UAF-1), residues 2-580
Descriptor: GOLD ION, PHOSPHATE ION, WD repeat-containing protein 48
Authors:HARRIS, S.F, YIN, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CVO
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BU of 5cvo by Molmil
WDR48:USP46~ubiquitin ternary complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.885 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
5CVN
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BU of 5cvn by Molmil
WDR48 (2-580):USP46~ubiquitin ternary complex
Descriptor: Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 46, WD repeat-containing protein 48, ...
Authors:Harris, S.F, Yin, J.
Deposit date:2015-07-27
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.36 Å)
Cite:Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.
Structure, 23, 2015
4MXV
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BU of 4mxv by Molmil
Structure of Lymphotoxin alpha bound to anti-LTa Fab
Descriptor: Lymphotoxin-alpha, anti-Lymphotoxin alpha antibody heavy chain, anti-Lymphotoxin alpha antibody light chain
Authors:Yin, J.P, Hymowitz, S.G.
Deposit date:2013-09-26
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction.
Proc.Natl.Acad.Sci.USA, 110, 2013
4MXW
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BU of 4mxw by Molmil
Structure of heterotrimeric lymphotoxin LTa1b2 bound to lymphotoxin beta receptor LTbR and anti-LTa Fab
Descriptor: Lymphotoxin-alpha, Lymphotoxin-beta, Tumor necrosis factor receptor superfamily member 3, ...
Authors:Sudhamsu, J, Yin, J.P, Hymowitz, S.G.
Deposit date:2013-09-26
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Dimerization of LT beta R by LT alpha 1 beta 2 is necessary and sufficient for signal transduction.
Proc.Natl.Acad.Sci.USA, 110, 2013
4NNO
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BU of 4nno by Molmil
Crystal Structure of Manganese ABC transporter substrate-binding protein MntC from Staphylococcus Aureus bound to a Zinc ion
Descriptor: Lipoprotein, ZINC ION
Authors:Rouge, L, Ahuja, S, Sudhamsu, J.
Deposit date:2013-11-18
Release date:2014-11-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.174 Å)
Cite:Structural analysis of bacterial ABC transporter inhibition by an antibody fragment.
Structure, 23, 2015
4NNP
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BU of 4nnp by Molmil
Crystal Structure of Apo Manganese ABC transporter MntC from Staphylococcus aureus bound to an antagonistic fab fragment
Descriptor: Heavy chain of antagonistic fab fragment, Light chain of antagonistic fab fragment, Lipoprotein
Authors:Rouge, L, Sudhamsu, J.
Deposit date:2013-11-18
Release date:2014-12-10
Last modified:2020-05-20
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Structural analysis of bacterial ABC transporter inhibition by an antibody fragment.
Structure, 23, 2015
4PO6
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BU of 4po6 by Molmil
Crystal structure of the human TYK2 FERM and SH2 domains with an IFNAR1 intracellular peptide
Descriptor: GLYCEROL, Interferon alpha/beta receptor 1, Non-receptor tyrosine-protein kinase TYK2
Authors:Wallweber, H.J.A, Lupardus, P.J.
Deposit date:2014-02-25
Release date:2014-04-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Structural basis of IFN receptor recognition by TYK2
Nat.Struct.Mol.Biol., 2014
3V56
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BU of 3v56 by Molmil
Re-refinement of PDB entry 1OSG - Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold - reveals an additonal copy of the peptide.
Descriptor: BR3 derived peptive, SULFATE ION, Tumor necrosis factor ligand superfamily member 13B
Authors:Smart, O.S, Womack, T.O, Flensburg, C, Keller, P, Sharff, A, Paciorek, W, Vonrhein, C, Bricogne, G.
Deposit date:2011-12-16
Release date:2012-03-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER.
Acta Crystallogr.,Sect.D, 68, 2012
4G3G
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BU of 4g3g by Molmil
Crystal structure of murine NF-kappaB inducing kinase (NIK) V408L bound to a 2-(aminothiazolyl)phenol (cmp3)
Descriptor: 4-fluoro-2-{[4-(pyridin-4-yl)-1,3-thiazol-2-yl]amino}phenol, NF-kappa-beta-inducing kinase
Authors:Hymowitz, S.
Deposit date:2012-07-13
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
4G3E
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BU of 4g3e by Molmil
Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 6-alkynylindoline (cmp1)
Descriptor: (2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydro-1H-indol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol, NF-kappa-beta-inducing kinase, SULFATE ION
Authors:Hymowitz, S.G, de Leon-Boenig, G.
Deposit date:2012-07-13
Release date:2012-08-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
4G3F
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BU of 4g3f by Molmil
Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 2-(aminothiazoly)phenol (cmp2)
Descriptor: 3-{2-[(5-fluoro-2-hydroxyphenyl)amino]-1,3-thiazol-4-yl}benzonitrile, NF-kappa-beta-inducing kinase
Authors:Hymowitz, S.G, de Leon-Boenig, G.
Deposit date:2012-07-13
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.642 Å)
Cite:The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
4G3D
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BU of 4g3d by Molmil
Crystal structure of human NF-kappaB inducing kinase (NIK)
Descriptor: MAGNESIUM ION, NF-kappa-beta-inducing kinase
Authors:Hymowitz, S.G, de Leon-Boenig, G.
Deposit date:2012-07-13
Release date:2012-08-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
4G3C
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BU of 4g3c by Molmil
Crystal structure of apo murine Nf-kappaB inducing kinase (NIK)
Descriptor: NF-kappa-beta-inducing kinase, SULFATE ION
Authors:Hymowitz, S.G, de Leon-Boenig, G.
Deposit date:2012-07-13
Release date:2012-08-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
1KMX
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BU of 1kmx by Molmil
Heparin-binding Domain from Vascular Endothelial Growth Factor
Descriptor: vascular endothelial growth factor
Authors:Stauffer, M.E, Skelton, N.J, Fairbrother, W.J.
Deposit date:2001-12-17
Release date:2002-07-24
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Refinement of the Solution Structure of the Heparin-binding Domain of Vascular Endothelial Growth Factor using Residual Dipolar Couplings
J.BIOMOL.NMR, 23, 2002
1N09
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BU of 1n09 by Molmil
A minimal beta-hairpin peptide scaffold for beta-turn display
Descriptor: bhpW, disulfide cyclized beta-hairpin peptide
Authors:Russell, S.J, Blandl, T, Skelton, N.J, Cochran, A.G.
Deposit date:2002-10-11
Release date:2003-02-04
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:Stability of cyclic beta-hairpins: asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair
J.Am.Chem.Soc., 125, 2003
1L6X
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BU of 1l6x by Molmil
FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OF THE B-DOMAIN FROM PROTEIN A CALLED Z34C
Descriptor: IMMUNOGLOBULIN GAMMA-1 HEAVY CHAIN CONSTANT REGION, Minimized B-domain of Protein A Z34C, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Idusogie, E.E, Presta, L.G, Santoro-Gazzano, H, Totpal, K, Wong, P.Y, Ultsch, M, Meng, Y.G, Mullkerrin, M.G.
Deposit date:2002-03-14
Release date:2002-04-10
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc.
J.Immunol., 164, 2000
1CRR
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BU of 1crr by Molmil
THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Kraulis, P.J, Domaille, P.J, Campbell-Burk, S.L, Van Aken, T, Laue, E.D.
Deposit date:1993-11-24
Release date:1994-07-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
1CRQ
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BU of 1crq by Molmil
THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Kraulis, P.J, Domaille, P.J, Campbell-Burk, S.L, Van Aken, T, Laue, E.D.
Deposit date:1993-11-24
Release date:1994-07-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
1CRP
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BU of 1crp by Molmil
THE SOLUTION STRUCTURE AND DYNAMICS OF RAS P21. GDP DETERMINED BY HETERONUCLEAR THREE AND FOUR DIMENSIONAL NMR SPECTROSCOPY
Descriptor: C-H-RAS P21 PROTEIN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Kraulis, P.J, Domaille, P.J, Campbell-Burk, S.L, Van Aken, T, Laue, E.D.
Deposit date:1993-11-24
Release date:1994-07-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy.
Biochemistry, 33, 1994
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