5CVO

WDR48:USP46~ubiquitin ternary complex

Summary for 5CVO

• Entry DOI: 10.2210/pdb5cvo/pdb
• Related: 5CVL 5CVM 5CVN
• Descriptor: WD repeat-containing protein 48, Ubiquitin carboxyl-terminal hydrolase 46, Polyubiquitin-B, ... (4 entities in total)
• Functional Keywords: wdr48, wd repeat, beta propeller, usp46, ubiquitin, covalent complex, dub, deubiquitinase, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (Human); More
• Cellular location: Nucleus: Q8TAF3; Ubiquitin: Cytoplasm : P0CG47
• Total number of polymer chains: 6
• Total formula weight: 251340.77

Authors

Harris, S.F.,Yin, J. (deposition date: 2015-07-27, release date: 2015-10-07, Last modification date: 2023-09-27)

• Primary citation: Yin, J.,Schoeffler, A.J.,Wickliffe, K.,Newton, K.,Starovasnik, M.A.,Dueber, E.C.,Harris, S.F.; Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46.; Structure, 23:2043-2054, 2015; PubMed: 26388029; DOI: 10.1016/j.str.2015.08.010

Experimental method

X-RAY DIFFRACTION (3.885 Å)