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1L3T
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BU of 1l3t by Molmil
Crystal Structure of Bacillus DNA Polymerase I Fragment product complex with 10 base pairs of duplex DNA following addition of a single dTTP residue
Descriptor: 5'-D(*GP*AP*CP*G*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3', 5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*T)-3', DNA Polymerase I, ...
Authors:Johnson, S.J, Taylor, J.S, Beese, L.S.
Deposit date:2002-03-01
Release date:2003-03-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA, 100, 2003
1XC9
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BU of 1xc9 by Molmil
Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA polymerase I, DNA primer strand, ...
Authors:Hsu, G.W, Huang, X, Luneva, N.P, Geacintov, N.E, Beese, L.S.
Deposit date:2004-09-01
Release date:2004-12-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication
J.Biol.Chem., 280, 2005
1LV5
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BU of 1lv5 by Molmil
Crystal Structure of the Closed Conformation of Bacillus DNA Polymerase I Fragment Bound to DNA and dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*TP*CP*GP*CP*TP*GP*AP*TP*CP*CP*G)-3', 5'-D(*GP*GP*AP*TP*CP*AP*GP*CP*GP*A)-3', ...
Authors:Johnson, S.J, Taylor, J.S, Beese, L.S.
Deposit date:2002-05-24
Release date:2003-03-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Processive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations
Proc.Natl.Acad.Sci.USA, 100, 2003
3HP6
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BU of 3hp6 by Molmil
Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus F710Y mutant bound to G:T mismatch
Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*CP*CP*GP*TP*GP*AP*TP*CP*G)-3', 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DDG))-3', ...
Authors:Wu, E.Y, Beese, L.S.
Deposit date:2009-06-03
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.
J.Biol.Chem., 286, 2011
3HPO
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BU of 3hpo by Molmil
Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus Y714S mutant bound to G:T mismatch
Descriptor: 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DOC))-3', 5'-D(P*GP*GP*CP*GP*TP*GP*AP*TP*CP*G)-3', DNA polymerase I, ...
Authors:Wu, E.Y, Beese, L.S.
Deposit date:2009-06-04
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.
J.Biol.Chem., 286, 2011
3HT3
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BU of 3ht3 by Molmil
Crystal structure of fragment DNA polymerase I from Bacillus stearothermophilus V713P mutant bound to G:dCTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*CP*GP*GP*CP*GP*TP*GP*AP*TP*CP*G)-3', 5'-D(*CP*GP*AP*TP*CP*AP*CP*GP*(DOC))-3', ...
Authors:Wu, E.Y, Beese, L.S.
Deposit date:2009-06-11
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.
J.Biol.Chem., 286, 2011
3BDP
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BU of 3bdp by Molmil
DNA POLYMERASE I/DNA COMPLEX
Descriptor: DNA (5'-D(*AP*GP*CP*AP*TP*CP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*AP*TP*GP*CP*2DT)-3'), PROTEIN (DNA POLYMERASE I), ...
Authors:Kiefer, J.R, Mao, C, Beese, L.S.
Deposit date:1997-11-17
Release date:1999-01-13
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal.
Nature, 391, 1998
7MXW
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BU of 7mxw by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (uf1)
Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.836 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXU
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BU of 7mxu by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' flap DNA (cf2)
Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*A)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.042 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXS
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BU of 7mxs by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cr)
Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.798 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXV
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BU of 7mxv by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (ur)
Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.211 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXX
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BU of 7mxx by Molmil
Crystal structure of human exonuclease 1 Exo1 (R92A) in complex with 5' flap DNA (uf4)
Descriptor: CALCIUM ION, DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*GP*AP*C)-3'), DNA (5'-D(P*TP*CP*TP*CP*GP*TP*CP*AP*CP*TP*AP*GP*CP*G)-3'), ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXQ
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BU of 7mxq by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-1)
Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXR
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BU of 7mxr by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (r-2)
Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*TP*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
7MXT
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BU of 7mxt by Molmil
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with 5' recessed-end DNA (cmr)
Descriptor: DNA (5'-D(*CP*GP*CP*TP*AP*GP*TP*CP*GP*AP*CP*AP*T)-3'), DNA (5'-D(P*CP*GP*AP*CP*TP*AP*GP*CP*G)-3'), Exonuclease 1, ...
Authors:Shi, Y, Beese, L.S.
Deposit date:2021-05-19
Release date:2023-05-10
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.048 Å)
Cite:Structures of reaction intermediates reveal transient Mg2+-binding events that dynamically coordinate Human Exonuclease I activities
To Be Published
2O8F
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BU of 2o8f by Molmil
human MutSalpha (MSH2/MSH6) bound to DNA with a single base T insert
Descriptor: 5'-D(*CP*GP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*CP*CP*GP*TP*C)-3', 5'-D(*GP*AP*CP*GP*GP*CP*CP*GP*CP*CP*GP*CP*TP*AP*GP*CP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8E
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BU of 2o8e by Molmil
human MutSalpha (MSH2/MSH6) bound to a G T mispair, with ADP bound to MSH2 only
Descriptor: 5'-D(*CP*CP*TP*AP*GP*CP*CP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*GP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8B
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BU of 2o8b by Molmil
human MutSalpha (MSH2/MSH6) bound to ADP and a G T mispair
Descriptor: 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8C
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BU of 2o8c by Molmil
human MutSalpha (MSH2/MSH6) bound to ADP and an O6-methyl-guanine T mispair
Descriptor: 5'-D(*CP*CP*TP*AP*GP*CP*GP*TP*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*(6OG)P*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.37 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
2O8D
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BU of 2o8d by Molmil
human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair
Descriptor: 5'-D(*CP*CP*TP*AP*GP*CP*GP*(DU)P*GP*CP*GP*GP*TP*TP*C)-3', 5'-D(*GP*AP*AP*CP*CP*GP*CP*GP*CP*GP*CP*TP*AP*GP*G)-3', ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Warren, J.J, Pohlhaus, T.J, Changela, A, Modrich, P.L, Beese, L.S.
Deposit date:2006-12-12
Release date:2007-06-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of the Human MutSalpha DNA Lesion Recognition Complex.
Mol.Cell, 26, 2007
1NK4
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BU of 1nk4 by Molmil
GUANINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ...
Authors:Johnson, S.J, Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NKB
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BU of 1nkb by Molmil
A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER THREE ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP, DGTP, AND DTTP.
Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ...
Authors:Johnson, S.J, Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NJY
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BU of 1njy by Molmil
THYMINE-THYMINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ...
Authors:Johnson, S.J, Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NKC
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BU of 1nkc by Molmil
A BACILLUS DNA POLYMERASE I PRODUCT COMPLEX BOUND TO A GUANINE-THYMINE MISMATCH AFTER FIVE ROUNDS OF PRIMER EXTENSION, FOLLOWING INCORPORATION OF DCTP, DGTP, DTTP, AND DATP.
Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ...
Authors:Johnson, S.J, Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
1NJX
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BU of 1njx by Molmil
THYMINE-GUANINE MISMATCH AT THE POLYMERASE ACTIVE SITE
Descriptor: DNA POLYMERASE I, DNA PRIMER STRAND, DNA TEMPLATE STRAND, ...
Authors:Johnson, S.J, Beese, L.S.
Deposit date:2003-01-02
Release date:2004-03-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structures of mismatch replication errors observed in a DNA polymerase.
Cell(Cambridge,Mass.), 116, 2004

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