1XC9

Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication

Summary for 1XC9

Entry DOI	10.2210/pdb1xc9/pdb
Related PRD ID	PRD_900003
Descriptor	DNA primer strand, DNA template strand with benzo[a]pyrene adduct, DNA polymerase I, ... (8 entities in total)
Functional Keywords	dna polymerase i; dna replication; klenow fragment; benzo[a]pyrene; benzopyrene; dna lesion; translation replication, transferase-dna complex, transferase/dna
Biological source	Geobacillus stearothermophilus
Total number of polymer chains	3
Total formula weight	74818.99
Authors	Hsu, G.W.,Huang, X.,Luneva, N.P.,Geacintov, N.E.,Beese, L.S. (deposition date: 2004-09-01, release date: 2004-12-14, Last modification date: 2023-08-23)
Primary citation	Hsu, G.W.,Huang, X.,Luneva, N.P.,Geacintov, N.E.,Beese, L.S. Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication J.Biol.Chem., 280:3764-3770, 2005 Cited by PubMed: 15548515 DOI: 10.1074/jbc.M411276200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation