Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
4N39
DownloadVisualize
BU of 4n39 by Molmil
Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26)
Descriptor: Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-5'-DIPHOSPHATE
Authors:Lazarus, M.B, Herr, W, Walker, S.
Deposit date:2013-10-06
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:HCF-1 is cleaved in the active site of O-GlcNAc transferase.
Science, 342, 2013
4MO4
DownloadVisualize
BU of 4mo4 by Molmil
Crystal structure of AnmK bound to AMPPCP
Descriptor: Anhydro-N-acetylmuramic acid kinase, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Bacik, J.P, Mark, B.L.
Deposit date:2013-09-11
Release date:2014-01-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle.
J.Biol.Chem., 289, 2014
4N3A
DownloadVisualize
BU of 4n3a by Molmil
Crystal Structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (1-26)E10A
Descriptor: Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-5'-DIPHOSPHATE
Authors:Lazarus, M.B, Herr, W, Walker, S.
Deposit date:2013-10-06
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:HCF-1 is cleaved in the active site of O-GlcNAc transferase.
Science, 342, 2013
4N3B
DownloadVisualize
BU of 4n3b by Molmil
Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26)E10Q and UDP-5SGlcNAc
Descriptor: (2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit
Authors:Lazarus, M.B, Herr, W, Walker, S.
Deposit date:2013-10-06
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:HCF-1 is cleaved in the active site of O-GlcNAc transferase.
Science, 342, 2013
4N3C
DownloadVisualize
BU of 4n3c by Molmil
Crystal Structure of human O-GlcNAc Transferase bound to a peptide from HCF-1 pro-repeat2(1-26) and UDP-GlcNAc
Descriptor: Host cell factor 1, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Lazarus, M.B, Herr, W, Walker, S.
Deposit date:2013-10-06
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:HCF-1 is cleaved in the active site of O-GlcNAc transferase.
Science, 342, 2013
7QQH
DownloadVisualize
BU of 7qqh by Molmil
Crystal structure of MYORG (D520N) in complex with Gal-a1,4-Glc
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Meek, R.W, Davies, G.J.
Deposit date:2022-01-07
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The primary familial brain calcification-associated protein MYORG is an alpha-galactosidase with restricted substrate specificity.
Plos Biol., 20, 2022
7QQG
DownloadVisualize
BU of 7qqg by Molmil
Crystal structure of MYORG bound to 1-deoxygalactonojirimycin
Descriptor: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Meek, R.W, Davies, G.J.
Deposit date:2022-01-07
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The primary familial brain calcification-associated protein MYORG is an alpha-galactosidase with restricted substrate specificity.
Plos Biol., 20, 2022
7QQF
DownloadVisualize
BU of 7qqf by Molmil
Crystal structure of unliganded MYORG
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
Authors:Meek, R.W, Davies, G.J.
Deposit date:2022-01-07
Release date:2022-08-31
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:The primary familial brain calcification-associated protein MYORG is an alpha-galactosidase with restricted substrate specificity.
Plos Biol., 20, 2022
8AX3
DownloadVisualize
BU of 8ax3 by Molmil
Structure of recombinant human beta-glucocerebrosidase in complex with L-carbaxylosyl fluoride
Descriptor: (1~{S},2~{R},3~{S},6~{S})-6-fluoranylcyclohex-4-ene-1,2,3-triol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rowland, R.J, Davies, G.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Single turnover covalent inhibitors for functional chaperoning of lysosomal glycoside hydrolases
To be published
8AWR
DownloadVisualize
BU of 8awr by Molmil
Structure of recombinant human beta-glucocerebrosidase in complex with L-carbaxylosyl chloride
Descriptor: (1~{S},2~{R},3~{S},6~{S})-6-chloranylcyclohex-4-ene-1,2,3-triol, (1~{S},2~{S},3~{S},4~{R})-cyclohexane-1,2,3,4-tetrol, 1,2-ETHANEDIOL, ...
Authors:Rowland, R.J, Davies, G.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Single turnover covalent inhibitors for functional chaperoning of lysosomal glycoside hydrolases
To be published
8AWK
DownloadVisualize
BU of 8awk by Molmil
Structure of recombinant human beta-glucocerebrosidase in complex with D-carbaxylosyl chloride
Descriptor: (2~{S},3~{S},4~{R})-cyclohex-5-ene-1,2,3,4-tetrol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Rowland, R.J, Davies, G.J.
Deposit date:2022-08-30
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Single turnover covalent inhibitors for functional chaperoning of lysosomal glycoside hydrolases
To be published
8BAC
DownloadVisualize
BU of 8bac by Molmil
Crystal structure of human heparanase in complex with competitive inhibitor GD05
Descriptor: (3S,4R,5R)-4,5-dihydroxypiperidine-3-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Armstrong, Z, Davies, G.J.
Deposit date:2022-10-11
Release date:2023-03-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of alpha-Iduronidase, beta-Glucuronidase and Heparanase.
Chembiochem, 24, 2023
4MO5
DownloadVisualize
BU of 4mo5 by Molmil
Crystal structure of AnmK bound to AMPPCP and anhMurNAc
Descriptor: 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, Anhydro-N-acetylmuramic acid kinase, MAGNESIUM ION, ...
Authors:Bacik, J.P, Mark, B.L.
Deposit date:2013-09-11
Release date:2014-01-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle.
J.Biol.Chem., 289, 2014
4MSS
DownloadVisualize
BU of 4mss by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-acetamido-4,5,6-trihydroxyazepane
Descriptor: Beta-hexosaminidase 1, GLYCEROL, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]acetamide
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2013-09-18
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Selective trihydroxyazepane NagZ inhibitors increase sensitivity of Pseudomonas aeruginosa to beta-lactams.
Chem.Commun.(Camb.), 49, 2013
5UTQ
DownloadVisualize
BU of 5utq by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to PUGNAc
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-hexosaminidase, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2017-02-15
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance.
Protein Sci., 26, 2017
5UTR
DownloadVisualize
BU of 5utr by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to (3S,4R,5R,6S)-3-butyryl-4,5,6-trihydroxyazepane
Descriptor: Beta-hexosaminidase, N-[(3S,4R,5R,6S)-4,5,6-trihydroxyazepan-3-yl]butanamide
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2017-02-15
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance.
Protein Sci., 26, 2017
5UTP
DownloadVisualize
BU of 5utp by Molmil
Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to N-ethylbutyryl-PUGNAc
Descriptor: Beta-hexosaminidase, N-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(phenylcarbamoyl)oxy]imino}tetrahydro-2H-pyran-3-yl]-2-ethylbutanamide
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2017-02-15
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance.
Protein Sci., 26, 2017
4AIS
DownloadVisualize
BU of 4ais by Molmil
A complex structure of BtGH84
Descriptor: GLYCEROL, GLYCOLIC ACID, O-GLCNACASE BT_4395
Authors:He, Y, Davies, G.J.
Deposit date:2012-02-13
Release date:2012-06-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase.
J.Biol.Chem., 287, 2012
4AIU
DownloadVisualize
BU of 4aiu by Molmil
A complex structure of BtGH84
Descriptor: (3AR,5R,6S,7R,7AR)-2,5-BIS(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]OXAZOLE-6,7-DIOL, CALCIUM ION, O-GLCNACASE BT_4395
Authors:He, Y, Davies, G.J.
Deposit date:2012-02-13
Release date:2012-06-20
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups: Intracellular Beta-O-Linked N-Glycolylglucosamine (Glcngc), Udp-Glcngc, and the Biochemical and Structural Rationale for the Substrate Tolerance of Beta-O-Linked Beta-N-Acetylglucosaminidase.
J.Biol.Chem., 287, 2012
4OJN
DownloadVisualize
BU of 4ojn by Molmil
Crystal structure of human muscle L-lactate dehydrogenase
Descriptor: GLYCEROL, L-lactate dehydrogenase A chain, PENTAETHYLENE GLYCOL
Authors:Kolappan, S, Craig, L.
Deposit date:2014-01-21
Release date:2014-12-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Acta Crystallogr.,Sect.D, 71, 2015
4OKN
DownloadVisualize
BU of 4okn by Molmil
Crystal structure of human muscle L-lactate dehydrogenase, ternary complex with NADH and oxalate
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, KANAMYCIN A, L-lactate dehydrogenase A chain, ...
Authors:Kolappan, S, Craig, L.
Deposit date:2014-01-22
Release date:2014-12-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Acta Crystallogr.,Sect.D, 71, 2015
4QT0
DownloadVisualize
BU of 4qt0 by Molmil
Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL)QUINOLIN-4-YL]AMINO}BENZOIC ACID
Descriptor: 3-{[3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl]amino}benzoic acid, L-lactate dehydrogenase A chain
Authors:Kolappan, S, Craig, L.
Deposit date:2014-07-06
Release date:2014-12-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Acta Crystallogr.,Sect.D, 71, 2015
4QSM
DownloadVisualize
BU of 4qsm by Molmil
Crystal structure of human muscle L-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid
Descriptor: 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3-sulfamoylquinolin-4-yl]amino}benzoic acid, L-lactate dehydrogenase A chain
Authors:Kolappan, S, Craig, L.
Deposit date:2014-07-06
Release date:2014-12-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Acta Crystallogr.,Sect.D, 71, 2015
2XJ7
DownloadVisualize
BU of 2xj7 by Molmil
BtGH84 in complex with 6-acetamido-6-deoxy-castanospermine
Descriptor: 6-ACETAMIDO-6-DEOXY-CASTANOSPERMINE, CALCIUM ION, O-GLCNACASE BT_4395
Authors:He, Y, Davies, G.J.
Deposit date:2010-07-02
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of O-Glcnacase Using a Potent and Cell-Permeable Inhibitor Does not Induce Insulin Resistance in 3T3-L1 Adipocytes.
Chem.Biol., 17, 2010
2VSN
DownloadVisualize
BU of 2vsn by Molmil
Structure and topological arrangement of an O-GlcNAc transferase homolog: insight into molecular control of intracellular glycosylation
Descriptor: URIDINE-5'-DIPHOSPHATE, XCOGT
Authors:Martinez-Fleites, C, Macauley, M.S, He, Y, Shen, D, Vocadlo, D, Davies, G.J.
Deposit date:2008-04-28
Release date:2008-06-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of an O-Glcnac Transferase Homolog Provides Insight Into Intracellular Glycosylation.
Nat.Struct.Mol.Biol., 15, 2008

221051

PDB entries from 2024-06-12

PDB statisticsPDBj update infoContact PDBjnumon