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5ULW
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BU of 5ulw by Molmil
Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine
Descriptor: CHLORIDE ION, DNA (5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA (5'-D(*TP*(MA7)P*GP*GP*GP*TP*CP*CP*T)-3'), ...
Authors:Jain, R, Aggarwal, A.K.
Deposit date:2017-01-25
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.617 Å)
Cite:Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-iota.
Sci Rep, 7, 2017
5WMB
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BU of 5wmb by Molmil
Structure of the 10S (-)-cis-BP-dG modified Rev1 ternary complex (the BP residue is disordered)
Descriptor: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
Authors:Rechkoblit, O, Kolbanovsky, A, Landes, H, Geacintov, N.E, Aggarwal, A.K.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.
Nat Commun, 8, 2017
5WM1
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BU of 5wm1 by Molmil
Structure of the 10S (+)-trans-BP-dG modified Rev1 ternary complex
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Rechkoblit, O, Kolbanovsky, A, Landes, H, Geacintov, N.E, Aggarwal, A.K.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.
Nat Commun, 8, 2017
5WM8
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BU of 5wm8 by Molmil
Structure of the 10R (+)-cis-BP-dG modified Rev1 ternary complex
Descriptor: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, ...
Authors:Rechkoblit, O, Kolbanovsky, A, Landes, H, Geacintov, N.E, Aggarwal, A.K.
Deposit date:2017-07-28
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Mechanism of error-free replication across benzo[a]pyrene stereoisomers by Rev1 DNA polymerase.
Nat Commun, 8, 2017
3PZP
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BU of 3pzp by Molmil
Human DNA polymerase kappa extending opposite a cis-syn thymine dimer
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*A)-3', 5'-D(*TP*TP*CP*CP*(TTD)P*GP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3', ...
Authors:Vasquez-Del Carpio, R, Silverstein, T.D, Lone, S, Johnson, R.E, Prakash, S, Prakash, L, Aggarwal, A.K.
Deposit date:2010-12-14
Release date:2011-12-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.336 Å)
Cite:Role of human DNA polymerase kappa in extension opposite from a cis-syn thymine dimer.
J.Mol.Biol., 408, 2011
3QU3
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BU of 3qu3 by Molmil
Crystal structure of IRF-7 DBD apo form
Descriptor: 1,2-ETHANEDIOL, Interferon regulatory factor 7, SODIUM ION
Authors:De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K.
Deposit date:2011-02-23
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Nucleic Acids Res., 39, 2011
3QU6
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BU of 3qu6 by Molmil
Crystal structure of IRF-3 DBD free form
Descriptor: CHLORIDE ION, IRF3 protein, SODIUM ION, ...
Authors:De Ioannes, P.E, Escalante, C.R, Aggarwal, A.K.
Deposit date:2011-02-23
Release date:2011-06-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding.
Nucleic Acids Res., 39, 2011
3TQ1
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BU of 3tq1 by Molmil
Human DNA Polymerase eta in binary complex with DNA
Descriptor: DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*TP*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA polymerase eta
Authors:Ummat, A, Silverstein, T.D, Jain, R, Buku, A, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
Deposit date:2011-09-08
Release date:2012-02-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.556 Å)
Cite:Human DNA Polymerase Eta Is Pre-Aligned for dNTP Binding and Catalysis.
J.Mol.Biol., 415, 2012
3OHB
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BU of 3ohb by Molmil
Yeast DNA polymerase eta extending from an 8-oxoG lesion
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(*TP*AP*AP*TP*GP*(8OG)P*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ...
Authors:Silverstein, T.D, Jain, R, Aggarwal, A.K.
Deposit date:2010-08-17
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Structure, 18, 2010
3MFI
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BU of 3mfi by Molmil
DNA Polymerase Eta in Complex With a cis-syn Thymidine Dimer
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(*TP*AP*AP*(TTD)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ...
Authors:Silverstein, T.D, Johnson, R.E, Jain, R, Prakash, L, Prakash, S, Aggarwal, A.K.
Deposit date:2010-04-02
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural basis for the suppression of skin cancers by DNA polymerase eta.
Nature, 465, 2010
3MFH
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BU of 3mfh by Molmil
DNA Polymerase Eta in Complex With Undamaged DNA
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(*TP*AP*AP*TP*TP*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ...
Authors:Silverstein, T.D, Johnson, R.E, Jain, R, Prakash, L, Prakash, S, Aggarwal, A.K.
Deposit date:2010-04-02
Release date:2010-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for the suppression of skin cancers by DNA polymerase eta.
Nature, 465, 2010
3OHA
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BU of 3oha by Molmil
Yeast DNA polymerase eta inserting dCTP opposite an 8oxoG lesion
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*GP*TP*CP*CP*TP*CP*CP*CP*CP*TP*(DOC))-3', 5'-D(P*TP*(8OG)P*GP*AP*GP*GP*GP*GP*AP*GP*GP*AP*C)-3', ...
Authors:Silverstein, T.D, Jain, R, Aggarwal, A.K.
Deposit date:2010-08-17
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Structure, 18, 2010
3OSP
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BU of 3osp by Molmil
Structure of rev1
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*(3DR)P*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ...
Authors:Nair, D.T, Aggarwal, A.K.
Deposit date:2010-09-09
Release date:2011-04-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:DNA synthesis across an abasic lesion by yeast REV1 DNA polymerase.
J.Mol.Biol., 406, 2011
3ODH
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BU of 3odh by Molmil
Structure of OkrAI/DNA complex
Descriptor: CALCIUM ION, DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), OkrAI endonuclease
Authors:Vanamee, E.S, Aggarwal, A.K.
Deposit date:2010-08-11
Release date:2010-10-06
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Asymmetric DNA recognition by the OkrAI endonuclease, an isoschizomer of BamHI.
Nucleic Acids Res., 39, 2011
1FOK
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BU of 1fok by Molmil
STRUCTURE OF RESTRICTION ENDONUCLEASE FOKI BOUND TO DNA
Descriptor: DNA (5'-D(*AP*TP*GP*AP*CP*TP*AP*GP*CP*GP*TP*TP*AP*TP*CP*AP*T P*CP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*GP*AP*TP*GP*AP*TP*AP*AP*CP*GP*CP*TP*AP*G P*TP*CP*A)-3'), PROTEIN (FOKI RESTRICTION ENDONUCLEASE)
Authors:Aggarwal, D.A, Wah, J.A, Hirsch, L.F, Dorner, I, Schildkraut, A.K.
Deposit date:1997-04-18
Release date:1997-12-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the multimodular endonuclease FokI bound to DNA.
Nature, 388, 1997
1IF1
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BU of 1if1 by Molmil
INTERFERON REGULATORY FACTOR 1 (IRF-1) COMPLEX WITH DNA
Descriptor: DNA (26-MER), PROTEIN (INTERFERON REGULATORY FACTOR 1)
Authors:Escalante, C.R, Yie, J, Thanos, D, Aggarwal, A.
Deposit date:1997-09-12
Release date:1998-02-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure of IRF-1 with bound DNA reveals determinants of interferon regulation.
Nature, 391, 1998
2LWD
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BU of 2lwd by Molmil
Solution structure of second CARD of human RIG-I
Descriptor: Probable ATP-dependent RNA helicase DDX58
Authors:Dutta, K, Ferrage, F, Aggarwal, A.
Deposit date:2012-07-27
Release date:2012-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation.
Structure, 20, 2012
2LWE
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BU of 2lwe by Molmil
Solution structure of mutant (T170E) second CARD of human RIG-I
Descriptor: Probable ATP-dependent RNA helicase DDX58
Authors:Dutta, K, Ferrage, F, Aggarwal, A.
Deposit date:2012-07-27
Release date:2012-10-31
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation.
Structure, 20, 2012
1ZET
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BU of 1zet by Molmil
X-ray data do not support hoogsteen base-pairing during replication by human polymerase iota
Descriptor: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(P*AP*GP*GP*GP*(BRU)P*CP*CP*(BRU)P*(BRU)P*CP*CP*CP*CP*C)-3', MAGNESIUM ION, ...
Authors:Wang, J.
Deposit date:2005-04-19
Release date:2005-07-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA polymerases: Hoogsteen base-pairing in DNA replication?
Nature, 437, 2005
1PER
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BU of 1per by Molmil
THE COMPLEX BETWEEN PHAGE 434 REPRESSION DNA-BINDING DOMAIN AND OPERATOR SITE OR3: STRUCTURAL DIFFERENCES BETWEEN CONSENSUS AND NON-CONSENSUS HALF-SITES
Descriptor: DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*GP*TP*TP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*AP*AP*CP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 REPRESSOR)
Authors:Rodgers, D.W, Harrison, S.C.
Deposit date:1993-11-09
Release date:1994-01-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The complex between phage 434 repressor DNA-binding domain and operator site OR3: structural differences between consensus and non-consensus half-sites.
Structure, 1, 1993
1JM4
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BU of 1jm4 by Molmil
NMR Structure of P/CAF Bromodomain in Complex with HIV-1 Tat Peptide
Descriptor: HIV-1 Tat Peptide, P300/CBP-associated Factor
Authors:Mujtaba, S, He, Y, Zeng, L, Farooq, A, Carlson, J.E, Ott, M, Verdin, E, Zhou, M.-M.
Deposit date:2001-07-17
Release date:2002-07-17
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain
Mol.Cell, 9, 2002
1LMB
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BU of 1lmb by Molmil
REFINED 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE LAMBDA REPRESSOR-OPERATOR COMPLEX
Descriptor: DNA (5'-D(*AP*AP*TP*AP*CP*CP*AP*CP*TP*GP*GP*CP*GP*GP*TP*GP*A P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*TP*CP*AP*CP*CP*GP*CP*CP*AP*GP*TP*GP*G P*TP*AP*T)-3'), PROTEIN (LAMBDA REPRESSOR)
Authors:Beamer, L.J, Pabo, C.O.
Deposit date:1991-11-05
Release date:1991-11-05
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined 1.8 A crystal structure of the lambda repressor-operator complex.
J.Mol.Biol., 227, 1992
3CRO
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BU of 3cro by Molmil
THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION
Descriptor: DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 CRO)
Authors:Mondragon, A, Harrison, S.C.
Deposit date:1990-07-06
Release date:1991-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The phage 434 Cro/OR1 complex at 2.5 A resolution.
J.Mol.Biol., 219, 1991

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