3TQ1

Human DNA Polymerase eta in binary complex with DNA

Summary for 3TQ1

• Entry DOI: 10.2210/pdb3tq1/pdb
• Descriptor: DNA polymerase eta, DNA (5'-D(*TP*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), DNA (5'-D(*TP*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... (4 entities in total)
• Functional Keywords: polymerase, dna replication, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: Q9Y253
• Total number of polymer chains: 3
• Total formula weight: 55318.16

Authors

Ummat, A.,Silverstein, T.D.,Jain, R.,Buku, A.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K. (deposition date: 2011-09-08, release date: 2012-02-08, Last modification date: 2024-02-28)

• Primary citation: Ummat, A.,Silverstein, T.D.,Jain, R.,Buku, A.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Human DNA Polymerase Eta Is Pre-Aligned for dNTP Binding and Catalysis.; J.Mol.Biol., 415:627-634, 2012; PubMed: 22154937; DOI: 10.1016/j.jmb.2011.11.038

Experimental method

X-RAY DIFFRACTION (2.556 Å)