5ULW

Structure of human DNA polymerase iota bound to template 1-methyl-deoxyadenosine

Summary for 5ULW

• Entry DOI: 10.2210/pdb5ulw/pdb
• Related: 5ULX
• Descriptor: DNA (5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3'), DNA (5'-D(*TP*(MA7)P*GP*GP*GP*TP*CP*CP*T)-3'), DNA polymerase iota, ... (7 entities in total)
• Functional Keywords: human dna polymerase iota n1-methyl-deoxyadenosine dttp tls, thansferase-dna complex, thansferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 53015.90

Authors

Jain, R.,Aggarwal, A.K. (deposition date: 2017-01-25, release date: 2017-04-19, Last modification date: 2023-10-04)

• Primary citation: Jain, R.,Choudhury, J.R.,Buku, A.,Johnson, R.E.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Mechanism of error-free DNA synthesis across N1-methyl-deoxyadenosine by human DNA polymerase-iota.; Sci Rep, 7:43904-43904, 2017; PubMed: 28272441; DOI: 10.1038/srep43904

Experimental method

X-RAY DIFFRACTION (2.617 Å)