1MQ6
| Crystal Structure of 3-chloro-N-[4-chloro-2-[[(5-chloro-2-pyridinyl)amino]carbonyl]-6-methoxyphenyl]-4-[[(4,5-dihydro-2-oxazolyl)methylamino]methyl]-2-thiophenecarboxamide Complexed with Human Factor Xa | Descriptor: | 3-CHLORO-N-[4-CHLORO-2-[[(5-CHLORO-2-PYRIDINYL)AMINO]CARBONYL]-6-METHOXYPHENYL]-4-[[(4,5-DIHYDRO-2-OXAZOLYL)METHYLAMINO]METHYL]-2-THIOPHENECARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR X HEAVY CHAIN, ... | Authors: | Adler, M, Whitlow, M. | Deposit date: | 2002-09-13 | Release date: | 2003-01-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structures of Two Potent Nonamidine Inhibitors Bound to Factor Xa Biochemistry, 41, 2002
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1MQ5
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3T4F
| Crystal Structure of a KGE Collagen Mimetic Peptide at 1.68 A | Descriptor: | collagen mimetic peptide | Authors: | Fallas, J.A, Dong, J, Miller, M.D, Tao, Y.J, Hartgerink, J.D. | Deposit date: | 2011-07-25 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural insights into charge pair interactions in triple helical collagen-like proteins. J.Biol.Chem., 287, 2012
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3U29
| Crystal Structure of a KGD Collagen Mimetic Peptide at 2.0 A | Descriptor: | collagen mimetic peptide | Authors: | Fallas, J.A, Dong, J, Miller, M.D, Tao, Y.J, Hartgerink, J.D. | Deposit date: | 2011-10-02 | Release date: | 2011-12-28 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural insights into charge pair interactions in triple helical collagen-like proteins. J.Biol.Chem., 287, 2012
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6JDE
| crystal structure of a DNA repair protein | Descriptor: | Putative DNA repair helicase RadD, ZINC ION | Authors: | Yan, X.X, Tang, Q. | Deposit date: | 2019-02-01 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a novel ATPase RadD from Escherichia coli. Proteins, 87, 2019
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6IWV
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6JGY
| Crystal structure of LASV-GP2 in a post fusion conformation | Descriptor: | Pre-glycoprotein polyprotein GP complex | Authors: | Zhu, Y, Zhang, X, Chen, B, Ye, S, Zhang, R. | Deposit date: | 2019-02-15 | Release date: | 2019-09-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.389 Å) | Cite: | Crystal Structure of Refolding Fusion Core of Lassa Virus GP2 and Design of Lassa Virus Fusion Inhibitors. Front Microbiol, 10, 2019
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6JRJ
| The structure of co-crystals of 8r-B-EGFR T790M/C797S complex | Descriptor: | 6-(2-chloranyl-3-fluoranyl-phenyl)-5-methyl-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one, Epidermal growth factor receptor | Authors: | Zhu, S.J, Yun, C.H. | Deposit date: | 2019-04-04 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.943 Å) | Cite: | Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S). J.Med.Chem., 62, 2019
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6JRK
| The structure of co-crystals of 8r-B-EGFR WT complex | Descriptor: | 6-(2-chloranyl-3-fluoranyl-phenyl)-5-methyl-2-[[3-methyl-4-(4-methylpiperazin-1-yl)phenyl]amino]-8-[(3S)-1-propanoylpiperidin-3-yl]pyrido[2,3-d]pyrimidin-7-one, Epidermal growth factor receptor | Authors: | Zhu, S.J, Yun, C.H. | Deposit date: | 2019-04-04 | Release date: | 2020-04-15 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Structure-Based Design of 5-Methylpyrimidopyridone Derivatives as New Wild-Type Sparing Inhibitors of the Epidermal Growth Factor Receptor Triple Mutant (EGFRL858R/T790M/C797S). J.Med.Chem., 62, 2019
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6M71
| SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors | Descriptor: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase | Authors: | Gao, Y, Yan, L, Huang, Y, Liu, F, Cao, L, Wang, T, Wang, Q, Lou, Z, Rao, Z. | Deposit date: | 2020-03-16 | Release date: | 2020-04-01 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure of the RNA-dependent RNA polymerase from COVID-19 virus. Science, 368, 2020
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6LXT
| Structure of post fusion core of 2019-nCoV S2 subunit | Descriptor: | Spike protein S2, TETRAETHYLENE GLYCOL, ZINC ION | Authors: | Zhu, Y, Sun, F. | Deposit date: | 2020-02-11 | Release date: | 2020-02-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion. Cell Res., 30, 2020
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2NV5
| Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD) | Descriptor: | PTPRD, PHOSPHATASE | Authors: | Bonanno, J.B, Gilmore, J, Bain, K.T, Iizuka, M, Xu, W, Wasserman, S, Smith, D, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2006-11-10 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural genomics of protein phosphatases. J.STRUCT.FUNCT.GENOM., 8, 2007
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2P8E
| Crystal structure of the serine/threonine phosphatase domain of human PPM1B | Descriptor: | MAGNESIUM ION, PPM1B beta isoform variant 6 | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Lau, C, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-03-22 | Release date: | 2007-04-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.816 Å) | Cite: | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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2P4U
| Crystal structure of acid phosphatase 1 (Acp1) from Mus musculus | Descriptor: | Acid phosphatase 1, PHOSPHATE ION | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Wu, B, Xu, W, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-03-13 | Release date: | 2007-03-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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7UF8
| Structure of CtdP in complex with penicimutamide E and NADP+ | Descriptor: | 1,2-ETHANEDIOL, CtdP, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Rivera, S, Liu, Z, Newmister, S.A, Gao, X, Sherman, D.H. | Deposit date: | 2022-03-22 | Release date: | 2023-02-22 | Last modified: | 2023-04-19 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An NmrA-like enzyme-catalysed redox-mediated Diels-Alder cycloaddition with anti-selectivity. Nat.Chem., 15, 2023
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7VY6
| Coxsackievirus B3(VP3-234N) incubate with CD55 at pH7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VXH
| Coxsackievirus B3 full particle at pH7.4 (VP3-234Q) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-12 | Release date: | 2022-01-19 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VYM
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7VXZ
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7VY0
| Coxsackievirus B3 full particle at pH7.4 (VP3-234N) | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7VYK
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7VYL
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7VY5
| Coxsackievirus B3 (VP3-234Q) incubation with CD55 at pH7.4 | Descriptor: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-13 | Release date: | 2022-01-19 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7W17
| Coxsackievirus B3 full particle at pH7.4 (VP3-234E) | Descriptor: | PALMITIC ACID, VP1, VP2, ... | Authors: | Wang, Q.L, Liu, C.C. | Deposit date: | 2021-11-19 | Release date: | 2022-01-19 | Last modified: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Molecular basis of differential receptor usage for naturally occurring CD55-binding and -nonbinding coxsackievirus B3 strains. Proc.Natl.Acad.Sci.USA, 119, 2022
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7W14
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