8UKS

RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry

Summary for 8UKS

Entry DOI	10.2210/pdb8uks/pdb
Descriptor	RNA, DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerases I, II, and III subunit RPABC5, ... (16 entities in total)
Functional Keywords	rna polymerase ii, elongation complex, fapy-dg, dna lesion, transcription, ctp, transcription-dna-rna complex, transcription/dna/rna
Biological source	Saccharomyces cerevisiae S288C More
Total number of polymer chains	13
Total formula weight	488035.13
Authors	Hou, P.,Oh, J.,Wang, D. (deposition date: 2023-10-15, release date: 2024-04-24)
Primary citation	Gao, S.,Hou, P.,Oh, J.,Wang, D.,Greenberg, M.M. Molecular Mechanism of RNA Polymerase II Transcriptional Mutagenesis by the Epimerizable DNA Lesion, Fapy·dG. J.Am.Chem.Soc., 146:6274-6282, 2024 Cited by PubMed: 38393762 DOI: 10.1021/jacs.3c14476 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation