8T60

CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation

This is a non-PDB format compatible entry.

Summary for 8T60

• Entry DOI: 10.2210/pdb8t60/pdb
• EMDB information: 41062
• Descriptor: Melibiose permease, Nb725_4, NabFab_H Chain, ... (5 entities in total)
• Functional Keywords: sugar transporter; cation-coupled symporter; na(+) binding; protein conformation; nanobodies; nabfab; cryoem, membrane proteins; protein-protein interaction, transport protein
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium; More
• Total number of polymer chains: 4
• Total formula weight: 117888.18

Authors

Guan, L. (deposition date: 2023-06-14, release date: 2024-02-28, Last modification date: 2024-03-06)

• Primary citation: Hariharan, P.,Shi, Y.,Katsube, S.,Willibal, K.,Burrows, N.D.,Mitchell, P.,Bakhtiiari, A.,Stanfield, S.,Pardon, E.,Kaback, H.R.,Liang, R.,Steyaert, J.,Viner, R.,Guan, L.; Mobile barrier mechanisms for Na + -coupled symport in an MFS sugar transporter.; Elife, 12:-, 2024; PubMed: 38381130; DOI: 10.7554/eLife.92462

Experimental method

ELECTRON MICROSCOPY (3.29 Å)