8SI6
Cryo-EM structure of TRPM7 in MSP2N2 nanodisc in complex with agonist naltriben in closed state
Summary for 8SI6
| Entry DOI | 10.2210/pdb8si6/pdb |
| Related | 8SI2 8SI3 8SI4 8SI5 |
| EMDB information | 40496 40497 40498 40499 40500 |
| Descriptor | Transient receptor potential cation channel subfamily M member 7, (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, ... (6 entities in total) |
| Functional Keywords | transient receptor potential m family member 7, trp, channel, trpm7, trp channels, membrane protein, magnesium channel, agonist, ligand, naltriben |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 4 |
| Total formula weight | 632395.08 |
| Authors | Nadezhdin, K.D.,Neuberger, A.,Sobolevsky, A.I. (deposition date: 2023-04-14, release date: 2023-05-17, Last modification date: 2023-05-24) |
| Primary citation | Nadezhdin, K.D.,Correia, L.,Narangoda, C.,Patel, D.S.,Neuberger, A.,Gudermann, T.,Kurnikova, M.G.,Chubanov, V.,Sobolevsky, A.I. Structural mechanisms of TRPM7 activation and inhibition. Nat Commun, 14:2639-2639, 2023 Cited by PubMed: 37156763DOI: 10.1038/s41467-023-38362-3 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.44 Å) |
Structure validation
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