8GDY

Crystal structure of the human PDI first domain with 9 mutations

Summary for 8GDY

Entry DOI	10.2210/pdb8gdy/pdb
Descriptor	Protein disulfide-isomerase, THIOCYANATE ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	pdi, isomerase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	31841.43
Authors	Forouhar, F.,Banayan, N.E.,Loughlin, B.L.,Singh, S.,Wong, V.,Hunt, H.S.,Handelman, S.K.,Price, N.,Hunt, J.F. (deposition date: 2023-03-06, release date: 2024-01-24, Last modification date: 2024-03-20)
Primary citation	Banayan, N.E.,Loughlin, B.J.,Singh, S.,Forouhar, F.,Lu, G.,Wong, K.H.,Neky, M.,Hunt, H.S.,Bateman Jr., L.B.,Tamez, A.,Handelman, S.K.,Price, W.N.,Hunt, J.F. Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution. Protein Sci., 33:e4898-e4898, 2024 Cited by PubMed: 38358135 DOI: 10.1002/pro.4898 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation