7EWR

Cryo-EM structure of human GPR158 in complex with RGS7-Gbeta5 in a 2:2:2 ratio

Summary for 7EWR

• Entry DOI: 10.2210/pdb7ewr/pdb
• Related: 7EWL 7EWP
• EMDB information: 31351 31360 31363 31363 31365 31366
• Descriptor: Regulator of G-protein signaling 7, Guanine nucleotide-binding protein subunit beta-5, Probable G-protein coupled receptor 158 (3 entities in total)
• Functional Keywords: gpcr, signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 465472.98

Authors

Kim, Y.,Jeong, E.,Jeong, J.,Cho, Y. (deposition date: 2021-05-26, release date: 2021-12-01, Last modification date: 2022-02-16)

• Primary citation: Jeong, E.,Kim, Y.,Jeong, J.,Cho, Y.; Structure of the class C orphan GPCR GPR158 in complex with RGS7-G beta 5.; Nat Commun, 12:6805-6805, 2021; PubMed: 34815401; DOI: 10.1038/s41467-021-27147-1

Experimental method

ELECTRON MICROSCOPY (4.7 Å)