6XWG
Crystal Structure of the Human RXR/RAR DNA-Binding Domain Heterodimer Bound to the Human RARb2 DR5 Response Element
Summary for 6XWG
Entry DOI | 10.2210/pdb6xwg/pdb |
Descriptor | RARb2 DR5 Response Element, 5'-3' strand, RARb2 DR5 Response Element, 3'-5' strand, Retinoic acid receptor RXR-alpha, ... (8 entities in total) |
Functional Keywords | protein-dna complex, nuclear receptor, transcription |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 34170.94 |
Authors | McEwen, A.G.,Poussin-Courmontagne, P.,Peluso-Iltis, C.,Rochel, N. (deposition date: 2020-01-23, release date: 2020-09-09, Last modification date: 2024-01-24) |
Primary citation | Osz, J.,McEwen, A.G.,Bourguet, M.,Przybilla, F.,Peluso-Iltis, C.,Poussin-Courmontagne, P.,Mely, Y.,Cianferani, S.,Jeffries, C.M.,Svergun, D.I.,Rochel, N. Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR. Nucleic Acids Res., 48:9969-9985, 2020 Cited by PubMed: 32974652DOI: 10.1093/nar/gkaa697 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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