5GDS
HIRUNORMS ARE TRUE HIRUDIN MIMETICS. THE CRYSTAL STRUCTURE OF HUMAN ALPHA-THROMBIN:HIRUNORM V COMPLEX
5GDS の概要
エントリーDOI | 10.2210/pdb5gds/pdb |
分子名称 | ALPHA-THROMBIN, HIRUNORM V, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
機能のキーワード | serine protease-inhibitor complex, thrombin, thrombin synthetic inhibitors, antithrombotics, hirunorms, hirudin-like binding mode, blood coagulation, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
由来する生物種 | Homo sapiens (human) 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 37056.17 |
構造登録者 | De Simone, G.,Lombardi, A.,Galdiero, S.,Nastri, F.,Della Morte, R.,Staiano, N.,Pedone, C.,Bolognesi, M.,Pavone, V. (登録日: 1997-07-17, 公開日: 1998-01-21, 最終更新日: 2023-08-09) |
主引用文献 | De Simone, G.,Lombardi, A.,Galdiero, S.,Nastri, F.,Della Morte, R.,Staiano, N.,Pedone, C.,Bolognesi, M.,Pavone, V. Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex. Protein Sci., 7:243-253, 1998 Cited by PubMed: 9521099主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.1 Å) |
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