4W93
Human pancreatic alpha-amylase in complex with montbretin A
Summary for 4W93
Entry DOI | 10.2210/pdb4w93/pdb |
Related | 1bsi 1cpu 1hny 4gqq 4gqr |
Descriptor | Pancreatic alpha-amylase, CALCIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | amylase, glucosyl hydrolase, enzyme inhibitor, diabetes, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 57235.89 |
Authors | Williams, L.K.,Caner, S.,Brayer, G.D. (deposition date: 2014-08-27, release date: 2015-07-15, Last modification date: 2023-12-27) |
Primary citation | Williams, L.K.,Zhang, X.,Caner, S.,Tysoe, C.,Nguyen, N.T.,Wicki, J.,Williams, D.E.,Coleman, J.,McNeill, J.H.,Yuen, V.,Andersen, R.J.,Withers, S.G.,Brayer, G.D. The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif. Nat.Chem.Biol., 11:691-696, 2015 Cited by PubMed: 26214255DOI: 10.1038/nchembio.1865 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.352 Å) |
Structure validation
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