4PVZ

Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2

4PVZ の概要

• エントリーDOI: 10.2210/pdb4pvz/pdb
• 関連するPDBエントリー: 1BK5 1EE4 1EE5
• 分子名称: Importin subunit alpha, Inner nuclear membrane protein HEH2 (3 entities in total)
• 機能のキーワード: armadillo repeated structure, nuclear import adapter, importin beta, nls-cargos, protein binding
• 由来する生物種: Saccharomyces cerevisiae S288c (Baker's yeast); 詳細
• 細胞内の位置: Cytoplasm, perinuclear region: Q02821; Nucleus inner membrane ; Single-pass membrane protein : Q03281
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 103550.49

構造登録者

Lokareddy, R.K.,Hapsari, A.R.,van Rheenen, M.,Bhardwaj, A.,Veenhoff, L.M.,Cingolani, C. (登録日: 2014-03-18, 公開日: 2015-08-26, 最終更新日: 2023-09-20)

• 主引用文献: Lokareddy, R.K.,Hapsari, R.A.,van Rheenen, M.,Pumroy, R.A.,Bhardwaj, A.,Steen, A.,Veenhoff, L.M.,Cingolani, G.; Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.; Structure, 23:1305-1316, 2015; PubMed: 26051712; DOI: 10.1016/j.str.2015.04.017

実験手法

X-RAY DIFFRACTION (2.5 Å)