4PVZ
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2
Summary for 4PVZ
Entry DOI | 10.2210/pdb4pvz/pdb |
Related | 1BK5 1EE4 1EE5 |
Descriptor | Importin subunit alpha, Inner nuclear membrane protein HEH2 (3 entities in total) |
Functional Keywords | armadillo repeated structure, nuclear import adapter, importin beta, nls-cargos, protein binding |
Biological source | Saccharomyces cerevisiae S288c (Baker's yeast) More |
Cellular location | Cytoplasm, perinuclear region: Q02821 Nucleus inner membrane ; Single-pass membrane protein : Q03281 |
Total number of polymer chains | 4 |
Total formula weight | 103550.49 |
Authors | Lokareddy, R.K.,Hapsari, A.R.,van Rheenen, M.,Bhardwaj, A.,Veenhoff, L.M.,Cingolani, C. (deposition date: 2014-03-18, release date: 2015-08-26, Last modification date: 2023-09-20) |
Primary citation | Lokareddy, R.K.,Hapsari, R.A.,van Rheenen, M.,Pumroy, R.A.,Bhardwaj, A.,Steen, A.,Veenhoff, L.M.,Cingolani, G. Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23:1305-1316, 2015 Cited by PubMed: 26051712DOI: 10.1016/j.str.2015.04.017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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