4JGC
Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC)
Summary for 4JGC
Entry DOI | 10.2210/pdb4jgc/pdb |
Related | 4FNC |
Descriptor | G/T mismatch-specific thymine DNA glycosylase, oligonucleotide, oligonucleotide containing 5-carboxylcytosine, ... (5 entities in total) |
Functional Keywords | 5-carboxylcytosine; thymine dna glycosylase; dna modification; dna 5mc oxidation; epigenetic regulation, dna demethylation, 5-carboxylcytosine, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: Q13569 |
Total number of polymer chains | 3 |
Total formula weight | 40302.75 |
Authors | Hashimoto, H.,Zhang, X.,Cheng, X. (deposition date: 2013-02-28, release date: 2013-05-29, Last modification date: 2023-09-20) |
Primary citation | Hashimoto, H.,Zhang, X.,Cheng, X. Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH. Dna Repair, 12:535-540, 2013 Cited by PubMed: 23680598DOI: 10.1016/j.dnarep.2013.04.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.582 Å) |
Structure validation
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