4JGC
Human TDG N140A mutant IN A COMPLEX WITH 5-carboxylcytosine (5caC)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | G/T mismatch-specific thymine DNA glycosylase | polymer | 204 | 23027.6 | 1 | UniProt (Q13569) Pfam (PF03167) In PDB | Homo sapiens (human) | Thymine-DNA glycosylase |
| 2 | C | oligonucleotide | polymer | 28 | 8646.6 | 1 | |||
| 3 | D | oligonucleotide containing 5-carboxylcytosine | polymer | 28 | 8473.4 | 1 | |||
| 4 | D | 4-amino-2-oxo-1,2-dihydropyrimidine-5-carboxylic acid | non-polymer | 155.1 | 1 | Chemie (1RT) | |||
| 5 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A: 111 - 308 (UniProt: Q13569)
| PDB | External Database | Details |
|---|---|---|
| Gly 105 | - | expression tag |
| Ser 106 | - | expression tag |
| His 107 | - | expression tag |
| Met 108 | - | expression tag |
| Ala 109 | - | expression tag |
| Ser 110 | - | expression tag |
| Ala 140 | Asn 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 40147.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 155.1 | |
| All* | Total formula weight | 40302.8 |
