4GFH
Topoisomerase II-DNA-AMPPNP complex
Summary for 4GFH
Entry DOI | 10.2210/pdb4gfh/pdb |
Related | 1PVG 3L4J 3L4K |
Descriptor | DNA topoisomerase 2, DNA (5'-D(P*CP*CP*TP*AP*CP*TP*GP*CP*TP*AP*C)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*TP*AP*GP*CP*AP*GP*TP*AP*GP*G)-3'), ... (7 entities in total) |
Functional Keywords | topoisomerase, protein-dna complex, dna supercoiling, dna replication, atp-binding, dna-binding, isomerase, nucleotide-binding, nucleus, phosphoprotein, isomerase-dna complex, isomerase/dna |
Biological source | Saccharomyces cerevisiae (Baker's yeast) |
Total number of polymer chains | 10 |
Total formula weight | 305578.14 |
Authors | Schmidt, B.H.,Osheroff, N.,Berger, J.M. (deposition date: 2012-08-03, release date: 2012-10-03, Last modification date: 2019-07-31) |
Primary citation | Schmidt, B.H.,Osheroff, N.,Berger, J.M. Structure of a topoisomerase II-DNA-nucleotide complex reveals a new control mechanism for ATPase activity. Nat.Struct.Mol.Biol., 19:1147-1154, 2012 Cited by PubMed: 23022727DOI: 10.1038/nsmb.2388 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.408 Å) |
Structure validation
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