1PVG
Crystal Structure of the ATPase region of Saccharomyces Cerevisiae topoisomerase II
Summary for 1PVG
Entry DOI | 10.2210/pdb1pvg/pdb |
Related | 1BGW 1BJT 1Q1D |
Descriptor | DNA topoisomerase II, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (4 entities in total) |
Functional Keywords | ghkl atpase domain, isomerase |
Biological source | Saccharomyces cerevisiae (baker's yeast) |
Cellular location | Nucleus: P06786 |
Total number of polymer chains | 2 |
Total formula weight | 98196.77 |
Authors | Classen, S.,Olland, S.,Berger, J.M. (deposition date: 2003-06-27, release date: 2003-08-26, Last modification date: 2017-10-11) |
Primary citation | Classen, S.,Olland, S.,Berger, J.M. Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187 Proc.Natl.Acad.Sci.USA, 100:10629-10634, 2003 Cited by PubMed: 12963818DOI: 10.1073/pnas.1832879100 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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