4G2O

Human Thymidylate Synthase M190K with bound Purpurogallin

Summary for 4G2O

• Entry DOI: 10.2210/pdb4g2o/pdb
• Related: 3EGY 3EHI 4G6W 4GD7
• Descriptor: Thymidylate synthase, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, SULFATE ION, ... (4 entities in total)
• Functional Keywords: methyltransferase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P04818
• Total number of polymer chains: 1
• Total formula weight: 36281.34

Authors

Celeste, L.R.,Lebioda, L. (deposition date: 2012-07-12, release date: 2013-07-17, Last modification date: 2023-09-13)

• Primary citation: Celeste, L.R.,Lovelace, L.L.,Lebioda, L.; Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin; To be Published,

Experimental method

X-RAY DIFFRACTION (2.25 Å)