4GD7

Wild-Type Human Thymidylate Synthase with bound Purpurogallin

Summary for 4GD7

• Entry DOI: 10.2210/pdb4gd7/pdb
• Related: 3EHI 4G2O 4G6W
• Descriptor: Thymidylate Synthase, 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, ... (5 entities in total)
• Functional Keywords: methyltransferase, transferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : P04818
• Total number of polymer chains: 1
• Total formula weight: 36517.60

Authors

Celeste, L.R.,Lebioda, L. (deposition date: 2012-07-31, release date: 2013-07-31, Last modification date: 2023-09-13)

• Primary citation: Lesa, C.R.,Leslie, L.L.,Lukasz, L.; Oxidation of Cysteine 195 of Huyman Thymidylate Synthase by Purpurogallin; To be published, 2012

Experimental method

X-RAY DIFFRACTION (2.29 Å)