4DUW
E. coli (lacZ) beta-galactosidase (G974A) in complex with allolactose
Summary for 4DUW
Entry DOI | 10.2210/pdb4duw/pdb |
Related | 1DP0 1JZ8 4DUV 4DUX |
Related PRD ID | PRD_900041 |
Descriptor | Beta-galactosidase, beta-D-galactopyranose-(1-6)-beta-D-glucopyranose, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | bi-functional enzyme, allolactose synthesis, tim barrel (alpha/beta barrel), jelly-roll barrel, immunoglobulin, beta supersandwich, beta-galactosidase, glycosidase, hydrolase |
Biological source | Escherichia coli |
Total number of polymer chains | 4 |
Total formula weight | 487027.41 |
Authors | Wheatley, R.W.,Lo, S.,Janzcewicz, L.J.,Dugdale, M.L.,Huber, R.E. (deposition date: 2012-02-22, release date: 2013-03-20, Last modification date: 2023-09-13) |
Primary citation | Wheatley, R.W.,Lo, S.,Jancewicz, L.J.,Dugdale, M.L.,Huber, R.E. Structural Explanation for Allolactose (lac operon inducer) Synthesis by lacZ beta-Galactosidase and the Evolutionary Relationship between Allolactose synthesis and the lac Repressor J.Biol.Chem., 288:12993-13005, 2013 Cited by PubMed: 23486479DOI: 10.1074/jbc.M113.455436 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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