4DUV

E. coli (lacZ) beta-galactosidase (G974A) 2-deoxy-galactosyl-enzyme and bis-Tris complex

Summary for 4DUV

• Entry DOI: 10.2210/pdb4duv/pdb
• Related: 1DP0 1JZ4 4DUW 4DUX
• Descriptor: Beta-galactosidase, 2-deoxy-alpha-D-galactopyranose, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (7 entities in total)
• Functional Keywords: bi-functional enzyme, allolactose synthesis, tim barrel (alpha/beta barrel), jelly-roll barrel, immunoglobulin, beta supersandwich, beta-galactosidase, glycosidase, hydrolase
• Biological source: Escherichia coli
• Total number of polymer chains: 4
• Total formula weight: 488143.23

Authors

Wheatley, R.W.,Lo, S.,Janzcewicz, L.J.,Dugdale, M.L.,Huber, R.E. (deposition date: 2012-02-22, release date: 2013-04-03, Last modification date: 2023-09-13)

• Primary citation: Wheatley, R.W.,Lo, S.,Janzcewicz, L.J.,Dugdale, M.L.,Huber, R.E.; The Glucose Acceptor site of lacZ beta-galactosidase for the synthesis of allolactose - the natural inducer of the lac operon; To be Published,

Experimental method

X-RAY DIFFRACTION (2.1 Å)