4DUX

E. coli (lacZ) beta-galactosidase (N460S) in complex with L-ribose

Summary for 4DUX

Entry DOI	10.2210/pdb4dux/pdb
Related	4DUV 4DUW
Descriptor	Beta-galactosidase, beta-L-ribopyranose, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	bi-functional enzyme, allolactose synthesis, tim barrel (alpha/beta barrel), jelly-roll barrel, immunoglobulin, beta supersandwich, beta-galactosidase, glycosidase, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	4
Total formula weight	485813.02
Authors	Wheatley, R.W.,Lo, S.,Janzcewicz, L.J.,Dugdale, M.L.,Huber, R.E. (deposition date: 2012-02-22, release date: 2013-03-20, Last modification date: 2023-09-13)
Primary citation	Wheatley, R.W.,Lo, S.,Jancewicz, L.J.,Dugdale, M.L.,Huber, R.E. Structural explanation for allolactose (lac operon inducer) synthesis by lacZ beta-galactosidase and the evolutionary relationship between allolactose synthesis and the lac repressor. J.Biol.Chem., 288:12993-13005, 2013 Cited by PubMed: 23486479 DOI: 10.1074/jbc.M113.455436 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation