4AQE
CRYSTAL STRUCTURE OF DEAFNESS ASSOCIATED MUTANT MOUSE CADHERIN-23 EC1- 2S70P AND PROTOCADHERIN-15 EC1-2 FORM I
Summary for 4AQE
Entry DOI | 10.2210/pdb4aqe/pdb |
Related | 2WBX 2WCP 2WD0 2WHV 4APX 4AQ8 4AQA |
Descriptor | CADHERIN-23, PROTOCADHERIN-15, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | cell adhesion, hearing, deafness, cdh23, pcdh15, heterophilic |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Cellular location | Cell membrane; Single-pass type I membrane protein (By similarity): Q99PF4 Q99PJ1 |
Total number of polymer chains | 2 |
Total formula weight | 51883.97 |
Authors | Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P. (deposition date: 2012-04-16, release date: 2012-11-07, Last modification date: 2023-12-20) |
Primary citation | Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P. Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction Nature, 492:128-, 2012 Cited by PubMed: 23135401DOI: 10.1038/NATURE11590 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.27 Å) |
Structure validation
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