2WD0

CRYSTAL STRUCTURE OF NONSYNDROMIC DEAFNESS (DFNB12) ASSOCIATED MUTANT D124G OF MOUSE CADHERIN-23 EC1-2

Summary for 2WD0

• Entry DOI: 10.2210/pdb2wd0/pdb
• Related: 2WBX 2WCP
• Descriptor: CADHERIN-23, CALCIUM ION, SODIUM ION, ... (5 entities in total)
• Functional Keywords: cell adhesion, hearing
• Biological source: MUS MUSCULUS (HOUSE MOUSE)
• Cellular location: Cell membrane; Single-pass type I membrane protein (By similarity): Q99PF4
• Total number of polymer chains: 2
• Total formula weight: 47989.61

Authors

Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P. (deposition date: 2009-03-18, release date: 2010-04-21, Last modification date: 2023-12-13)

• Primary citation: Sotomayor, M.,Weihofen, W.,Gaudet, R.,Corey, D.P.; Structural Determinants of Cadherin-23 Function in Hearing and Deafness.; Neuron, 66:85-, 2010; PubMed: 20399731; DOI: 10.1016/J.NEURON.2010.03.028

Experimental method

X-RAY DIFFRACTION (2.74 Å)