3WU1
Crystal structure of the ETS1-RUNX1-DNA ternary complex
Summary for 3WU1
Entry DOI | 10.2210/pdb3wu1/pdb |
Related | 3WTS 3WTT 3WTU 3WTV 3WTW 3WTX 3WTY 3WTZ 3WU0 |
Descriptor | Runt-related transcription factor 1, Protein C-ets-1, DNA (5'-D(*GP*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*T)-3'), ... (5 entities in total) |
Functional Keywords | protein-dna complex, dna-binding, methylation, nucleus, phosphoprotein, transcription regulation, isopeptide bond, proto-oncogene, transcription-dna complex, transcription/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus : Q03347 Cytoplasm : P14921 |
Total number of polymer chains | 4 |
Total formula weight | 36308.63 |
Authors | Tahirov, T.H.,Ogata, K. (deposition date: 2014-04-21, release date: 2014-08-20, Last modification date: 2023-11-08) |
Primary citation | Shiina, M.,Hamada, K.,Inoue-Bungo, T.,Shimamura, M.,Uchiyama, A.,Baba, S.,Sato, K.,Yamamoto, M.,Ogata, K. A novel allosteric mechanism on protein-DNA interactions underlying the phosphorylation-dependent regulation of Ets1 target gene expressions. J.Mol.Biol., 427:1655-1669, 2015 Cited by PubMed: 25083921DOI: 10.1016/j.jmb.2014.07.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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