3O4S
Crystal Structure of HePTP with a Closed WPD Loop and an Ordered E-Loop
Summary for 3O4S
Entry DOI | 10.2210/pdb3o4s/pdb |
Related | 1ZC0 2GP0 2HVL 2QDC 2QDM 2QDP 3D42 3D44 3O4T 3O4U |
Descriptor | Tyrosine-protein phosphatase non-receptor type 7, SULFATE ION, GLYCEROL, ... (4 entities in total) |
Functional Keywords | heptp, human hematopoietic tyrosine phosphatase catalytic domain mutant, lc-ptp, ptpn7, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P35236 |
Total number of polymer chains | 1 |
Total formula weight | 36269.65 |
Authors | Critton, D.A.,Page, R. (deposition date: 2010-07-27, release date: 2010-11-24, Last modification date: 2023-09-06) |
Primary citation | Critton, D.A.,Tautz, L.,Page, R. Visualizing active-site dynamics in single crystals of HePTP: opening of the WPD loop involves coordinated movement of the E loop. J.Mol.Biol., 405:619-629, 2011 Cited by PubMed: 21094165DOI: 10.1016/j.jmb.2010.11.020 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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