2QDC

Crystal structure of the HePTP catalytic domain D236A mutant

Summary for 2QDC

Entry DOI	10.2210/pdb2qdc/pdb
Related	1zc0 2gp0 2hvl
Descriptor	Tyrosine-protein phosphatase non-receptor type 7, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	heptp, human hematopoietic tyrosine phosphatase catalytic domain mutant, lc-ptp, ptpn7, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P35236
Total number of polymer chains	1
Total formula weight	35666.11
Authors	Critton, D.A.,Tortajada, A.,Page, R. (deposition date: 2007-06-20, release date: 2008-06-24, Last modification date: 2023-09-20)
Primary citation	Critton, D.A.,Tortajada, A.,Stetson, G.,Peti, W.,Page, R. Structural basis of substrate recognition by hematopoietic tyrosine phosphatase. Biochemistry, 47:13336-13345, 2008 Cited by PubMed: 19053285 DOI: 10.1021/bi801724n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation