3LFV
crystal structure of unliganded PDE5A GAF domain
Summary for 3LFV
Entry DOI | 10.2210/pdb3lfv/pdb |
Related | 3MF0 |
Descriptor | cGMP-specific 3',5'-cyclic phosphodiesterase (1 entity in total) |
Functional Keywords | gaf, cgmp signaling, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 97724.94 |
Authors | Wang, H.,Robinson, H.,Ke, H. (deposition date: 2010-01-18, release date: 2010-09-22, Last modification date: 2024-02-21) |
Primary citation | Wang, H.,Robinson, H.,Ke, H. Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain. J.Biol.Chem., 285:38149-38156, 2010 Cited by PubMed: 20861010DOI: 10.1074/jbc.M110.141614 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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