3ICK
Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with minodronate and isopentenyl disphosphate
Summary for 3ICK
Entry DOI | 10.2210/pdb3ick/pdb |
Related | 3IBA 3ICM 3ICN 3ICZ 3ID0 |
Descriptor | Farnesyl pyrophosphate synthase, ACETIC ACID, (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), ... (7 entities in total) |
Functional Keywords | farnesyl diphosphate synthase, fpps, bisphosphonate, zoledronate, risedronate, minodronate, chagas disease, isoprene biosynthesis, transferase |
Biological source | Trypanosoma cruzi |
Total number of polymer chains | 1 |
Total formula weight | 42118.66 |
Authors | Amzel, L.M.,Huang, C.H.,Gabelli, S.B.,Oldfield, E. (deposition date: 2009-07-17, release date: 2010-02-09, Last modification date: 2024-02-21) |
Primary citation | Huang, C.H.,Gabelli, S.B.,Oldfield, E.,Amzel, L.M. Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78:888-899, 2010 Cited by PubMed: 19876942DOI: 10.1002/prot.22614 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report