3ID0

Trypanosoma cruzi farnesyl diphosphate synthase homodimer in complex with 3-Fluoro-1-(2-hydroxy-2,2-bisphosphono-ethyl)pyridinium

Summary for 3ID0

Entry DOI	10.2210/pdb3id0/pdb
Related	1YHK 1YHL 1YHM 3IBA 3ICK 3ICM 3ICN 3ICZ
Descriptor	Farnesyl pyrophosphate synthase, 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	farnesyl diphosphate synthase, fpps, bisphosphonate, zoledronate, risedronate, minodronate, chagas disease, isoprene biosynthesis, transferase
Biological source	Trypanosoma cruzi
Total number of polymer chains	1
Total formula weight	41792.48
Authors	Amzel, L.M.,Huang, C.H.,Gabelli, S.B.,Oldfield, E. (deposition date: 2009-07-19, release date: 2010-02-09, Last modification date: 2024-02-21)
Primary citation	Huang, C.H.,Gabelli, S.B.,Oldfield, E.,Amzel, L.M. Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. Proteins, 78:888-899, 2010 Cited by PubMed: 19876942 DOI: 10.1002/prot.22614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation