2NN1
Structure of inhibitor binding to Carbonic Anhydrase I
Summary for 2NN1
Entry DOI | 10.2210/pdb2nn1/pdb |
Related | 2NMX 2NN7 2NNG 2NNO 2NNS 2NNV |
Descriptor | Carbonic anhydrase 1, ZINC ION, 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID, ... (6 entities in total) |
Functional Keywords | zinc metalloenzyme, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00915 |
Total number of polymer chains | 2 |
Total formula weight | 58284.43 |
Authors | Christianson, D.W.,Jude, K.M. (deposition date: 2006-10-23, release date: 2007-04-24, Last modification date: 2023-08-30) |
Primary citation | Srivastava, D.K.,Jude, K.M.,Banerjee, A.L.,Haldar, M.,Manokaran, S.,Kooren, J.,Mallik, S.,Christianson, D.W. Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II J.Am.Chem.Soc., 129:5528-5537, 2007 Cited by PubMed: 17407288DOI: 10.1021/ja068359w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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