2NMX

Structure of inhibitor binding to Carbonic Anhydrase I

Summary for 2NMX

Entry DOI	10.2210/pdb2nmx/pdb
Related	2NN1 2NN7 2NNG 2NNO 2NNS 2NNV
Descriptor	Carbonic anhydrase 1, ZINC ION, N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE, ... (6 entities in total)
Functional Keywords	metalloenzyme, hydro lyase, lyase
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: P00915
Total number of polymer chains	2
Total formula weight	58310.52
Authors	Christianson, D.W.,Jude, K.M. (deposition date: 2006-10-23, release date: 2007-04-24, Last modification date: 2023-08-30)
Primary citation	Srivastava, D.K.,Jude, K.M.,Banerjee, A.L.,Haldar, M.,Manokaran, S.,Kooren, J.,Mallik, S.,Christianson, D.W. Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II J.Am.Chem.Soc., 129:5528-5537, 2007 Cited by PubMed: 17407288 DOI: 10.1021/ja068359w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation