2NNS
Structure of inhibitor binding to Carbonic Anhydrase II
Summary for 2NNS
| Entry DOI | 10.2210/pdb2nns/pdb |
| Related | 2NMX 2NN1 2NN7 2NNG 2NNO 2NNV |
| Descriptor | Carbonic anhydrase 2, ZINC ION, CHLORIDE ION, ... (6 entities in total) |
| Functional Keywords | zinc metalloenzyme, sulfonamide, lyase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 30181.22 |
| Authors | Christianson, D.W.,Jude, K.M. (deposition date: 2006-10-24, release date: 2007-05-08, Last modification date: 2023-08-30) |
| Primary citation | Srivastava, D.K.,Jude, K.M.,Banerjee, A.L.,Haldar, M.,Manokaran, S.,Kooren, J.,Mallik, S.,Christianson, D.W. Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II. J.Am.Chem.Soc., 129:5528-5537, 2007 Cited by PubMed: 17407288DOI: 10.1021/ja068359w PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.03 Å) |
Structure validation
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