2HTF

The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain

2HTF の概要

• エントリーDOI: 10.2210/pdb2htf/pdb
• NMR情報: BMRB: 7259
• 分子名称: DNA polymerase mu (1 entity in total)
• 機能のキーワード: brct domain, alpha-beta-alpha sandwich, transferase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus (By similarity): Q9NP87
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11420.02

構造登録者

DeRose, E.F.,Clarkson, M.W.,Gilmore, S.A.,Ramsden, D.A.,Mueller, G.A.,London, R.E.,Lee, A.L. (登録日: 2006-07-25, 公開日: 2007-02-27, 最終更新日: 2022-03-09)

• 主引用文献: DeRose, E.F.,Clarkson, M.W.,Gilmore, S.A.,Galban, C.J.,Tripathy, A.,Havener, J.M.,Mueller, G.A.,Ramsden, D.A.,London, R.E.,Lee, A.L.; Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.; Biochemistry, 46:12100-12110, 2007; PubMed: 17915942; DOI: 10.1021/bi7007728

実験手法

SOLUTION NMR