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The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain

Summary for 2HTF

DescriptorDNA polymerase mu (E.C.
Functional KeywordsBRCT domain, alpha-beta-alpha sandwich, TRANSFERASE,TRANSFERASE
Biological sourceHomo sapiens (human)
Cellular locationNucleus (By similarity) Q9NP87 
Total number of polymer chains1
Total molecular weight11420.11
DeRose, E.F.,Clarkson, M.W.,Gilmore, S.A.,Ramsden, D.A.,Mueller, G.A.,London, R.E.,Lee, A.L. (deposition date: 2006-07-25, release date: 2007-02-27, modification date: 2009-02-24)
Primary citation
DeRose, E.F.,Clarkson, M.W.,Gilmore, S.A.,Galban, C.J.,Tripathy, A.,Havener, J.M.,Mueller, G.A.,Ramsden, D.A.,London, R.E.,Lee, A.L.
Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.
Biochemistry, 46:12100-12110, 2007
PubMed: 17915942
DOI: 10.1021/bi7007728
MImport into Mendeley
Experimental method
NMR Information

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entries available on 2015-02-25
00:00 UTC / 09:00 JST