1ZJD

Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Kunitz Protease Inhibitor Domain of Protease Nexin II

1ZJD の概要

• エントリーDOI: 10.2210/pdb1zjd/pdb
• 関連するPDBエントリー: 1ZHM 1ZHP 1ZHR
• 分子名称: Catalytic Domain of Coagulation Factor XI, Kunitz Protease Inhibitory Domain of Protease Nexin II (3 entities in total)
• 機能のキーワード: coagulation factor xi; kunitz protease inhibitory domain; nexin ii, hydrolase, blood clotting
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P03951; Membrane; Single-pass type I membrane protein: P05067
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32988.32

構造登録者

Jin, L.,Navaneetham, D.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Walsh, P.N.,Abdel-Meguid, S.S. (登録日: 2005-04-28, 公開日: 2005-08-09, 最終更新日: 2023-08-23)

• 主引用文献: Navaneetham, D.,Jin, L.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Abdel-Meguid, S.S.,Walsh, P.N.; Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2; J.Biol.Chem., 280:36165-36175, 2005; PubMed: 16085935; DOI: 10.1074/jbc.M504990200

実験手法

X-RAY DIFFRACTION (2.6 Å)