1ZJD
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with Kunitz Protease Inhibitor Domain of Protease Nexin II
Summary for 1ZJD
Entry DOI | 10.2210/pdb1zjd/pdb |
Related | 1ZHM 1ZHP 1ZHR |
Descriptor | Catalytic Domain of Coagulation Factor XI, Kunitz Protease Inhibitory Domain of Protease Nexin II (3 entities in total) |
Functional Keywords | coagulation factor xi; kunitz protease inhibitory domain; nexin ii, hydrolase, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P03951 Membrane; Single-pass type I membrane protein: P05067 |
Total number of polymer chains | 2 |
Total formula weight | 32988.32 |
Authors | Jin, L.,Navaneetham, D.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Walsh, P.N.,Abdel-Meguid, S.S. (deposition date: 2005-04-28, release date: 2005-08-09, Last modification date: 2023-08-23) |
Primary citation | Navaneetham, D.,Jin, L.,Pandey, P.,Strickler, J.E.,Babine, R.E.,Abdel-Meguid, S.S.,Walsh, P.N. Structural and Mutational Analyses of the Molecular Interactions between the Catalytic Domain of Factor XIa and the Kunitz Protease Inhibitor Domain of Protease Nexin 2 J.Biol.Chem., 280:36165-36175, 2005 Cited by PubMed: 16085935DOI: 10.1074/jbc.M504990200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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