1XIW

Crystal structure of human CD3-e/d dimer in complex with a UCHT1 single-chain antibody fragment

1XIW の概要

• エントリーDOI: 10.2210/pdb1xiw/pdb
• 分子名称: T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 delta chain, immunoglobulin light chain variable region, ... (5 entities in total)
• 機能のキーワード: cd3-epsilon, cd3-delta, ucht1-scfv, immunoglobulin fold, antibody-antigen complex, membrane protein-immune system complex, membrane protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane ; Single-pass type I membrane protein : P07766 P04234
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 93288.08

構造登録者

Arnett, K.L.,Harrison, S.C.,Wiley, D.C. (登録日: 2004-09-22, 公開日: 2004-11-16, 最終更新日: 2023-08-23)

• 主引用文献: Arnett, K.L.,Harrison, S.C.,Wiley, D.C.; Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.; Proc.Natl.Acad.Sci.USA, 101:16268-16273, 2004; PubMed: 15534202; DOI: 10.1073/pnas.0407359101

実験手法

X-RAY DIFFRACTION (1.9 Å)