Crystal structure of human CD3-e/d dimer in complex with a UCHT1 single-chain antibody fragment

Summary for 1XIW

DescriptorT-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 delta chain, immunoglobulin light chain variable region, immunoglobulin heavy chain variable region
Functional KeywordsCD3-epsilon, CD3-delta, UCHT1-scFv, immunoglobulin fold, antibody-antigen complex, membrane protein-Immune System COMPLEX,membrane protein/Immune System
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P07766 P04234
Total number of polymer chains8
Total molecular weight93288.74
Arnett, K.L.,Harrison, S.C.,Wiley, D.C. (deposition date: 2004-09-22, release date: 2004-11-16, modification date: 2009-02-24)
Primary citation
Arnett, K.L.,Harrison, S.C.,Wiley, D.C.
Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.
Proc.Natl.Acad.Sci.USA, 101:16268-16273, 2004
PubMed: 15534202
DOI: 10.1073/pnas.0407359101
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24070.5%1.0%3.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

no rotation
rotated about x axis by 90°
rotated about y axis by 90°
Copyright © 2013-2015 Protein Data Bank Japan