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1XIW

Crystal structure of human CD3-e/d dimer in complex with a UCHT1 single-chain antibody fragment

Summary for 1XIW

DescriptorT-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 delta chain, immunoglobulin light chain variable region, immunoglobulin heavy chain variable region
Functional KeywordsCD3-epsilon, CD3-delta, UCHT1-scFv, immunoglobulin fold, antibody-antigen complex, membrane protein-Immune System COMPLEX,membrane protein/Immune System
Biological sourceHomo sapiens (human)
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Cellular locationMembrane; Single-pass type I membrane protein Membrane; Single-pass type I membrane protein 
Organ source
Total number of polymer chains8
Total molecular weight93288.74
Authors
Arnett, K.L.,Harrison, S.C.,Wiley, D.C. (deposition date: 2004-09-22, release date: 2004-11-16, modification date: 2009-02-24)
Primary citation
Arnett, K.L.,Harrison, S.C.,Wiley, D.C.
Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment.
Proc.Natl.Acad.Sci.USA, 101:16268-16273, 2004
PubMed: 15534202
DOI: 10.1073/pnas.0407359101
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)

More Asymmetric unit images

no rotation
rotated about x axis by 90°
rotated about y axis by 90°
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103735
entries available on 2014-10-01
00:00 UTC / 09:00 JST