1WWW

NGF IN COMPLEX WITH DOMAIN 5 OF THE TRKA RECEPTOR

1WWW の概要

• エントリーDOI: 10.2210/pdb1www/pdb
• 分子名称: PROTEIN (NERVE GROWTH FACTOR), PROTEIN (TRKA RECEPTOR) (3 entities in total)
• 機能のキーワード: complex, trka receptor, nerve growth factor, cysteine knot, immunoglobulin like domain, nerve growth factor-trka complex complex, nerve growth factor/trka complex
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P01138; Cell membrane; Single-pass type I membrane protein (By similarity): P04629
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 49245.74

構造登録者

Wiesmann, C.,Ultsch, M.H.,De Vos, A.M. (登録日: 1999-03-12, 公開日: 1999-09-15, 最終更新日: 2023-08-23)

• 主引用文献: Wiesmann, C.,Ultsch, M.H.,Bass, S.H.,de Vos, A.M.; Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor.; Nature, 401:184-188, 1999; PubMed: 10490030; DOI: 10.1038/43705

実験手法

X-RAY DIFFRACTION (2.2 Å)