1T3F
THREE DIMENSIONAL STRUCTURE OF A HUMANIZED ANTI-IFN-GAMMA FAB (HuZAF) IN P21 21 21 SPACE GROUP
Summary for 1T3F
Entry DOI | 10.2210/pdb1t3f/pdb |
Related | 1B2W 1B4J 1T04 |
Descriptor | Huzaf antibody light chain, Huzaf antibody heavy chain (3 entities in total) |
Functional Keywords | antibody engineering, humanized and chimeric antibody, fab, gamma-interferon, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 46911.18 |
Authors | Bourne, P.C.,Terzyan, S.S.,Cloud, G.,Landolfi, N.F.,Vasquez, M.,Edmundson, A.B. (deposition date: 2004-04-26, release date: 2004-10-05, Last modification date: 2023-08-23) |
Primary citation | Bourne, P.C.,Terzyan, S.S.,Cloud, G.,Landolfi, N.F.,Vasquez, M.,Edmundson, A.B. Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms. Acta Crystallogr.,Sect.D, 60:1761-1769, 2004 Cited by PubMed: 15388922DOI: 10.1107/S0907444904018670 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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